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KMID : 0355220080330010009
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Journal of Korean Academy Oral Medicine
2008 Volume.33 No. 1 p.9 ~ p.14
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Detection of Helicobacter Pylori in Saliva of Korean Infant
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Ryu Ji-Won
Lee Jang-Keun
Lee Young-Su
Yoon Chang-Lyuk
Ahn Jong-Mo
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Abstract
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Helicobacter pylori(H. pylori) has been associated with the cause of peptic ulcer and gastric cancer. H. pylori infection occur mostly during childhood and increase by aging. In route of transmission, Oral cavity does important role. So we employed this study to elucidate route of transmission by detection of H. pylori in infant saliva. We investigated 20 infants aged below 10 years and 20 teens aged below 20 years as study group and 71 adults aged 20 and over years as control group. H. pylori DNA was isolated from 5(25%) infants aged below 10 years, 6(30%) teens and 17(23.9%) adults by nested polymerase chain reaction(n-PCR). There was no statistically significant difference(P＞0.05). The obtained results suggest that H. pylori infection is relatively common in saliva of Korean infant and oral cavity may be reservoir of H. pylori.
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KEYWORD
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Helicobacter pylori, H.Pylori infection, Infant, Saliva
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